Interference with nutrient absorption

How coffee can influence the absorption of key nutrients, which nutrients are most affected, and practical strategies to minimize negative impacts.

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Article 8 of 12 in Coffee & Health/
Interference with nutrient absorption

Nutrients Affected by Coffee

  • Iron (non-heme iron):

  • Polyphenols (chlorogenic acids, tannins) bind to iron in plant-based foods.

  • Reduces absorption by up to 40–60% when consumed with meals.

  • Most significant for vegetarians, vegans, and individuals with low iron status.

  • Calcium:

  • Caffeine may increase urinary calcium excretion.

  • Effect is small (~4–6 mg calcium lost per 100 mg caffeine).

  • Usually not a concern with adequate dietary calcium.

  • Magnesium & Zinc:

  • Some evidence of mild reduction in absorption due to polyphenols.

  • Effects less pronounced than for iron.

Timing Matters

  • Coffee consumed with meals reduces iron absorption the most.
  • Drinking coffee 1–2 hours after meals significantly lowers this effect.
  • Adding milk to coffee may slightly reduce inhibitory effects on iron.

Practical Strategies

  • For individuals at risk of iron deficiency (pregnant women, children, vegetarians):
  • Avoid coffee/tea with iron-rich meals.
  • Combine iron sources with vitamin C (enhances absorption).
  • Maintain balanced calcium intake if consuming multiple coffees daily.
  • Diversify mineral intake across the day.

Summary

Coffee’s polyphenols can reduce absorption of non-heme iron and, to a lesser extent, calcium, magnesium, and zinc. The effect is most significant when consumed with meals. Simple timing strategies—such as enjoying coffee between meals—help minimize risks while preserving coffee’s health benefits.

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